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There are inadequate studies in pregnant women. There is no evidence of impaired fertility or teratogenicity from animal studies. Caution should be exercised in use in pregnancy, and the benefits weighed against the potential hazard. In cases where cefazolin was administered prior to caesarean section, cord blood levels were 25-33% maternal levels. There appeared to be no adverse effect on the foetus.
Very low concentrations of cefazolin have been found in breast milk. Caution should be exercised, and it is preferable to discontinue breastfeeding.
