Ethacrynic Acid: On the basis of animal studies, concurrent use may increase the risk of renal toxicity. This may occur with any potent diuretic.
Frusemide: On the basis of animal studies, concurrent use may increase the risk of renal toxicity. This may occur with any potent diuretic.
Probenecid: Concurrent use may result in increased and prolonged blood levels of cefazolin, probably due to decreased renal tubular secretion of cefazolin.
Laboratory Tests: Test for glucose in the urine, using Benedict's, Fehling's solutions or copper sulphate test tablets, may give false positive results. This does not occur with specific glucose oxidase test methods.
False positive Coombs' test results may occur, these can also occur in neonates where cephalosporins were administered to the mother predelivery.
Incompatibilities: Use of cefazolin sodium in a mixture with other antibiotics, including aminoglycosides, is not recommended.