FDA Pregnancy Category B: Reproductive studies performed in the mouse, rat, and rabbit were given Cloxacillin have revealed no evidence of impaired fertility or harm to the foetus.
Breastfeeding: Penicillins are distributed into breast milk, some in low concentrations. Although significant problems in humans have not been documented, the use of penicillins by nursing mothers may lead to sensitization, diarrhoea, candidiasis, and skin rash in the infant.