Intentional overdosing of Meronem is unlikely, although overdosing could occur particularly in patients with renal impairment. Limited post-marketing experience indicates that if adverse events occur following over dosage, they are consistent with the adverse event profile described in Adverse Reactions, are generally mild in severity and resolve on withdrawal or dose reduction. Symptomatic treatments should be considered.
In normal individuals rapid renal elimination will occur. Hemodialysis will remove Meronem IV and its metabolite.