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Constitution and Compatibility: Meronem IV to be used for bolus IV injection should be constituted with sterile water for injections (10 mL/500 mg). This provides an approximate available concentration of 50 mg/mL. Constituted solutions are clear or pale yellow.
For IV infusion Meronem vials may be directly constituted with a compatible infusion fluid (see Storage) and then further diluted with the compatible infusion fluid, as needed.
Freshly prepared solutions of Meronem IV should be used whenever possible. However, constituted solutions of Meronem IV maintain satisfactory potency at room temperature (15-25°C) or under refrigeration (4°C).
Meronem should not be mixed with or physically added to solutions containing other drugs. Solutions of Meronem should not be frozen.
Instructions for Use/Handling: Standard aseptic technique should be employed during constitution. Shake constituted solution before use.
All vials are for single use only.
