Moxilen Indications/Uses

"Moxilen" is a broad spectrum antibiotic indicated for the treatment of commonly occurring bacterial infections such as: Upper respiratory tract infections e.g. ear, nose and throat infections, otitis media.
Lower respiratory tract infections e.g. acute exacerbations of chronic bronchitis, lobar and bronchopneumonia.
Gastrointestinal tract infections e.g. typhoid and paratyphoid fever.
Genito-urinary tract infections e.g. cystitis, urethritis, pyelonephritis, bacteriuria in pregnancy, septic abortion, puerperal sepsis.
Skin and soft tissue infections.
Billiary tract infections.
Bone infections.
Pelvic infections.
Gonorrhoea (non-penicillinase producing strains).
Septicaemia.
Endocarditis.
Meningitis.
Peritonitis.
Dental abscess (as an adjunct to surgical management).
Helicobacter pylori eradication in peptic (duodenal and gastric) ulcer disease.
Infections such as septicaemia, endocarditis and meningitis due to susceptible organisms should be treated initially with high doses of a parenteral therapy and, where appropriate, in combination with another antibiotic.
Prophylaxis of endocarditis: "Moxilen" may be used for the prevention of bacteraemia associated with procedures such as dental extraction, in patients at risk of developing endocarditis. Strains of the following organisms are generally sensitive to the bactericidal action of "Moxilen" in vitro: Gram-positive: Aerobes: Emerococcus faecalis, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus viridans, penicillin-sensitive Staphylococcus aureus, Corynebacterium species, Bacillus anthracis, Listeria monocytogenes.
Anaerobes: Clostridium species.
Gram-negative: Aerobes: Haemophilus influenzae, Eschericia coli, Proteus mirabilis, Salmonella species, Shigella species, Bordetella pertussis, Brucella species, Neisseria gonorrhoeae, Neisseria meningitidis, Pasteurella septica, Vibrio cholerae, Helicobacter pylori.
Amoxicillin is susceptible to degradation by beta-lactamases and therefore the spectrum of activity of Moxilen does not include organisms which produce these enzymes, including resistant staphylococci and all strains of Pseudomonas, Klebsiella and Enterobacter.