Xilone Side Effects

Fluid and Electrolyte Disturbances: Congestive heart failure in susceptible patients, fluid retention, hypokalemic alkalosis, potassium loss and sodium retention.
CNS: Vertigo, convulsions, headache and psychic disturbances.
Cardiovascular: Hypertension, thrombophlebitis, thrombo-embolism, tachycardia and congestive heart failure.
Ophthalmology: Exophthalmos, glaucoma, increased intraocular pressure, blurred vision and cataracts.
GIT: Peptic ulcer with possible perforation and hemorrhage, ulcerative esophagitis, diarrhea, nausea, abdominal distention, increased appetite, pancreatitis and perforation of the small and large bowel particularly in patients with inflammatory bowel disease.
Metabolism: Negative nitrogen balance due to protein catabolism, growth suppression in children and decreased glucose tolerance.
Musculoskeletal: Fracture of long bones, steroid myopathy, tendon rupture, vertebral compression fractures, osteoporosis, aseptic necrosis of femoral and humeral heads, muscle weakness and loss of muscle mass.
Skin: Increased sweating, poor wound healing, ecchymosis, bruising, petechiae, striae, thin fragile skin and suppression of skin test reactions.
Endocrine: Decreased carbohydrate tolerance, development of cushingoid state, hirsutism, increased requirements for insulin or oral hypoglycemic agents in diabetes, manifestations of latent diabetes mellitus, menstrual irregularities, adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery or illness and suppression of growth in children.