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Pregnancy: Use of this medicine should be avoided, as a precautionary measure, during the first trimester of pregnancy, and should only be prescribed thereafter if necessary, limited to occasional use in the 3rd trimester.
If this medicinal product is administered at the end of pregnancy, monitoring of neurological and gastrointestinal function in the newborn appears to be warranted.
Lactation: Since antihistamines are excreted into breast-milk, although in small quantities, and owing to the marked sedative properties of promethazine, this medicinal product should be avoided in breast-feeding women.
