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The interaction described as follows are related to the presence of promethazine.
Inadvisable Combinations: Alcohol: Alcohol enhances the sedative effect of antihistamines.
Impaired alertness can make driving or machine operation dangerous.
The consumption of alcoholic beverages and alcohol-containing medicinal products is to be avoided.
Sultopride: Increase risk of ventricular rhythm disorders, particularly torsades de pointes, by addition of electrophysiological effects.
Combinations to be taken into account: Other central nervous system depressants: (sedative antidepressants, barbiturates, clonidine and related substances, hypnotics, morphine derivatives (analgesics and antitussives), methadone, neuroleptics, anxiolytics): Enhancement of central depression.
Impaired alertness can make driving or machine operation dangerous.
Atropine and other atropine substances: (imipramine antidepressants, anticholinergic antiparkinsonians, atropine antispasmodics, disopyramide, phenothiazine neuroleptics): Addition of adverse atropine effects such as urine retention, constipation, dry mouth.
