This medicines is contraindicated in the following cases: History of hypersensitivity to one of the components (particularly to parabens); Infants under two years of age; Because of the presence of promethazine hydrochloride: Hypersensitivity to antihistamines, History of agranulocytosis, Risk of urine retention related to urethral or prostate disorders, Risk of angle-closure glaucoma.
Use of this medicine is generally inadvisable in combination with sultopride.