Ofcin Dosage/Direction for Use

Urinary Tract Infections: 200-400 mg daily, preferably in the morning, and increased if necessary in upper urinary tract infections to 400 mg twice daily for 7-10 days.
Lower Respiratory Tract Infections: 400 mg daily, preferably in the morning, and increased if necessary to 400 mg twice daily for 7-14 days.
Skin and Soft Tissue Infections: 200-400 mg twice daily for 7 days.
Uncomplicated Gonorrhoea: 400 mg as a single dose.
Nongonococcal Urethritis and Cervicitis: 400 mg daily in single or divided doses for 7-10 days.
Renal Impairment: When creatinine clearance is 20-50 mL/min, the dosage should be reduced by ½ (100-200 mg). If creatinine clearance is <20 mL/min, 100 mg should be given every 24 hrs. In patients undergoing haemodialysis or peritoneal dialysis, 100 mg should be given every 24 hrs.
Liver Impairment: Dose of ofloxacin should be reduced accordingly in patients with impaired liver function.