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Symptoms: Cases of overdosage with Amoxicillin and Clavulanic acid are usually asymptomatic. If encountered gastrointestinal symptoms and disturbances of the fluid and electrolyte balances may be evident.
Treatment: They may be treated symptomatically with attention to the water electrolyte balance. Amoxicillin and Clavulanic acid can be removed from the circulation by haemodialysis. During the administration of high doses of Amoxicillin and Clavulanic acid adequate fluid intake and urinary output should be maintained to minimize the possibility of amoxicillin crystalluria.
