Dosages for the treatment of infection: Adults and children over 12 years: Usually 1.2 g 8 hourly. In more serious infections increase frequency to 6-hourly intervals.
Children 3 months-12 years: 30 mg/kg Amoxicillin and Clavulanic acid 8 hourly. In more serious infections, increase frequency to 6-hourly intervals.
Children 0-3 months: 30 mg/kg Amoxicillin and Clavulanic acid 12 hours in premature infants and in full-term infants during the perinatal period, increasing to 8 hours thereafter.
Dosage in renal impairment: Adults: (See table.)
Click on icon to see table/diagram/image
Children: Similar reductions in dosage should be made for children.
Dosage in hepatic impairment: Dose with caution; monitor hepatic function at regular intervals.
There are, as yet, insufficient data on which to base a dosage recommendation.
Each 1.2g vial of Amoxicillin and Clavulanic acid contains 1.0 mmol of potassium and 2.7 mmol of sodium (approx).
Route of administration: Intravenous route only.
Duration of therapy should be appropriate to the indication and should not exceed 14 days without review.