Clamentin Caution For Usage

Clamentin Powder for Injection: Stability and compatibility: Satisfactory antibiotic concentrations are retained at 5°C and at room temperature (25°C) in the recommended volumes of the following infusion fluids. If reconstituted and maintained at room temperature, infusions should be completed within the times stated as Table 3. (See Table 3).

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Reconstituted solutions should not be frozen.
Clamentin is less stable in infusions containing glucose, dextran or bicarbonate.
Reconstituted solutions should therefore not be added to such infusions but may be injected into the drip tubing over a period of 3-4 min.
If Clamentin IV is prescribed concurrently with an aminoglycoside, the antibiotics should not be mixed in the syringe, IV fluid container or given set because loss of activity of the aminoglycoside can occur under these conditions.
For storage at 5°C, the reconstituted solution should be added to pre-refrigerated infusion bags which can be stored for up to 8 hrs. Thereafter, the infusion should be administered immediately after reaching room temperature.