Prolonged or repeated therapy may result in bacterial or fungal overgrowth of nonsusceptible organisms. If superinfection occurs, Borymycin should be discontinued and appropriate therapy instituted.
Degradation products of minocycline are highly nephrotoxic and on occasion may produce Falconi-like syndrome. Therefore, caution should be taken not to use outdated products.
Borymycin should be avoided in patients with systemic lupus erythematosus as execerbations have been reported.
Care is advisable in patients with myasthenia gravis who may be at risk of neuromuscular blockade.
Increased sensitivity of skin to sunlight may occur.