Penicillin interferes with the antibacterial action of minocycline.
Antacids, iron, sodium bicarbonate, colestipol may impair absorption of Borymycin.
Dose reduction of anticoagulant may be required if it is administered concomitantly with minocycline.
Borymycin may decrease the effect of oral contraceptives; it may enhance methoxyflurane-induced nephrotoxicity.