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Common name: Deferasirox.
Chemical name: 4-[3,5-bis-(2-hydroxyphenyl)-[1,2,4]-triazol-1-yl]benzoic acid.
Molecular formula: C21H15N3O4.
Molecular mass: 373.37.
Physicochemical properties: white to slightly yellow powder.
Solubility: 0.4 mg/mL at pH 7.40, 25ºC.
pH: The pH of a 0.5% (m/V) suspension of deferasirox in water at 22-25°C is 4.10.
Excipients/Inactive Ingredients: core tablet: colloidal silicon dioxide, crospovidone, magnesium stearate, microcrystalline cellulose, poloxamer (188), povidone (K30); film-coating material: FD&C blue #2/Indigo carminine aluminum lake, hypromellose, polyethylene glycol (4000), talc, titanium dioxide.
