Voluven

Voluven

hydroxyethyl starch

Manufacturer:

Fresenius Kabi

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Per 1,000 mL Hydroxyethyl starch (130/0.4) 60 g, NaCl 9 g
Indications/Uses
Hypovolemia caused by acute blood loss. Elective surgery & trauma patients, patients undergoing open-heart surgery in association w/ cardiopulmonary bypass, where alternative infusion solutions are insufficient.
Dosage/Direction for Use
IV infusion Adult  Initially 10-20 mL infused slowly. Max dose: 50 mL/kg/day. Childn 2-12 yr including newborn & infant <2 yr 16±9 mL/kg.
Contraindications
Hypersensitivity. Severe sepsis, critically ill patients. Conditions where vol overload is a potential problem especially in cases of pulmonary oedema & congestive cardiac failure. Pre-existing coagulation or bleeding disorders. Intracranial bleeding, severe hypernatraemia or hyperchloraemia. Severe liver disease & renal impairment. Patients w/ burns, scalds & receiving dialysis treatment.
Special Precautions
Elective surgery & trauma patients. Anaphylactic reactions. Avoid use in patients w/ pre-existing renal dysfunction. Discontinue use at the 1st sign of clinically relevant renal injury & relevant coagulopathy. Continue monitoring of renal function in hospitalized patients for at least 90 days. Monitor coagulation status in patients undergoing open heart surgery in association w/ cardiopulmonary bypass & liver function. Avoid fluid overload; assess fluid status & rate of infusion regularly during treatment especially in patients w/ cardiac insufficiency. Ensure sufficient fluid is to be administered. Electrolyte abnormalities. Pregnancy & lactation.
Adverse Reactions
Pruritus; dilution of blood components eg, coagulation factors & other plasma protein, decreased hematocrit when using high doses.
MIMS Class
Intravenous & Other Sterile Solutions
ATC Classification
B05AA07 - hydroxyethylstarch ; Belongs to the class of blood substitutes and plasma protein fractions. Used as blood substitutes.
Presentation/Packing
Form
Voluven infusion 6 %
Packing/Price
500 mL x 1's
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