Do not use HES products in: Patients with severe sepsis; critically ill patients; patients with severe liver disease; patients with known hypersensitivity to hydroxyethyl starch; clinical conditions where volume overload is a potential problem, especially in cases of pulmonary oedema and congestive cardiac failure; patients with pre-existing coagulation or bleeding disorders; patients with renal impairment; patients receiving dialysis treatment; patients with severe hypernatraemia or severe hyperchloraemia; patients with intracranial bleeding; patients with blood coagulation disorders; patients with burns, scalds.