Hypertension: In the ambulatory patient, initiate therapy in grdually increasing dosages; adjust according to individual response. Start with 10 mg 4 times daily for the first 2 to 4 days, increasing to 25 mg 4 times daily for balance of first week. For second and subsequent weeks, increase dosage to a maximum of 50 mg 4 times daily. For maintenance, adjust dosage to lowest effective levels. In combination with other hypotensive agents, lower dosages of hydralazine may be considered.