Klorfen Dosage/Direction for Use

Adults: Should receive 50 mg/kg/day in divided doses at 6 hourly intervals, in exceptional cases, patients with infections due to moderately resistant organisms may require increased dosage up to 100 mg/kg/day to achieve blood levels required to inhibit the pathogens, but these high doses should be decreased as soon as possible. Dosage should be adjusted in patients with liver and renal impairment.
Children: Dosage of 50 mg/kg/day divided into 4 doses at 6 hourly intervals yields blood level in the range effective against most susceptible organisms. Severe infections eg, bacteremia or meningitis, especially when adequate cerebrospinal fluid concentrations are desired, may require dosage up to 100 mg/kg/day; however, it is recommended that dosage be reduced to 50 mg/kg/day as soon as possible. The injection is preferably given intravenous route. If intravenous injection is not possible, it could also be administered by intramuscular injection.