Capsule: Symptomatic response to OMEPAC 20 therapy does not preclude the presence of gastric malignancy. Unless benefits of the treatment outweigh the possible risks, the use of OMEPAC 20 in pregnant and lactating women is not recommended since there are no adequate or well-controlled studies regarding the usage of Omeprazole in such patients. Safely and effectiveness of Omeprazole in children has also not been established.
Injection: Before giving Omeprazole or other proton pump inhibitors to patients with gastric ulcers the possibility of malignancy should be considered since these drugs may mask symptoms and delay diagnosis. Omeprazole and other proton pump inhibitors should be used with caution in hepatic impairment.
Omeprazole should not be given during pregnancy and lactation, unless its use is considered essential.