Nurocol Special Precautions

FC Tablet: Citicoline may cause hypotension and in case necessary the hypotensive effect can be treated with corticosteroids or sympathomimetics.
In case of persistent intracranial hemorrhage, it is recommended not to exceed the dose of 1000 mg of citicoline daily, in very slow intravenous administration (30 drops/minute).
Peculiarities in usage: Citicoline preparation should be administered with caution to patients who suffer from trimethylaminuria, Parkinson's disease and patients with depression in anamnesis.
Injection: General: For patients with acute, severe and progressive disturbance of consciousness resulting from a head injury or brain operation, Citicoline injection should be administered in conjunction with haemostatics and an intracranial pressure relieving drug, or a treatment such as hypothermia. For patients with disturbance of consciousness in the acute stage of cerebral infarction, it is recommended to start the administration of Citicoline injection within 2 weeks after an apoplectic stroke.
In administering Citicoline injection intramuscularly, caution should be exercised so as not to affect the tissues, nerves, etc. Intramuscular injection should be given only when indispensable, and should be restricted to the minimum to be required. In particular, repeated injection at the same site should be avoided. Care should be exercised to avoid injection at sites along the course of the nerves. In case of intense pain or backflow of blood upon insertion of the injection needle, the needle should be withdrawn immediately and injected at a different site. In intravenous administration, inject as slowly as possible. Since shock may occur, a close observation should be maintained. If any such abnormalities such as drop in blood pressure, distressed feeling of the chest or dyspnoea are observed, Citicoline injection should be discontinued and appropriate measures taken.
Persistent Intracranial Haemorrhage: In case of persistent intracranial haemorrhage, it is recommended not to exceed the dose of 1,000 mg of Citicoline daily, given through very slow intravenous administration (30 drops/minute).
Use in Pregnancy & Lactation: FC Tablet: Preparation administration during pregnancy and lactation period is possible only in case when expected benefit for a mother overweighs a potential risk for a fetus or baby.
Use in Children: FC Tablet: There is no sufficient data concerning Citicoline administration to children, therefore Citicoline should not be administered to this age group of patients.
Use in Elderly: Injection: No dosage adjustment is required in this patient population and the usually recommended adult dose can be administered.