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FC Tablet: Intoxication appearance is unlikely due to low toxicity, even in cases when the therapeutic doses are accidentally exceeded. In case of accidental overdose a symptomatic therapy is carried out.
Injection: Citicoline exhibits very low toxicity profile in humans. In a short term, placebo-controlled, cross-over study, 12 healthy adults took Citicoline at daily doses of 600 and 1000 mg or placebo for consecutive five-day periods. Transient headaches occurred in four subjects on 600-mg dose, five on the 1000-mg dose, and one in placebo. No changes or abnormalities were observed in hematology, clinical biochemistry or neurological test.
