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Zavicefta is a white to yellow sterile powder.
Each vial contains ceftazidime (as pentahydrate) equivalent to 2000 mg ceftazidime and avibactam (as sodium salt) equivalent to 500 mg avibactam.
After reconstitution, 1 mL of solution contains 167.3 mg of ceftazidime (CAZ) and 41.8 mg of avibactam (AVI).
Ceftazidime (as pentahydrate) is a white to almost white crystalline powder. It is soluble in acid, alkali and dimethyl sulphoxide and slightly soluble in water, methanol and dimethylformamide.
Avibactam (as sodium) is a crystalline powder. It is freely soluble in water, relatively soluble in methanol and insoluble in ethanol.
The reconstituted solution is a clear and colourless to yellow solution free from visible particulate matter.
Excipients with known effect: Each vial contains approximately 6.44 mmol of sodium (approximately 148 mg).
Excipient/Inactive Ingredient: Anhydrous sodium carbonate.
