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Use in Pregnancy: Meclozine is classified by FDA as category B. There are no adequate and well-controlled studies in pregnant women or animals studies which have shown an adverse effect. This means that it is not expected to harm an unborn baby.
Pyridoxine is classified by FDA as category A. Therefore, it is considered to be safe for use during pregnancy. Pyridoxine requirements increase during pregnancy.
Use in Lactation: Meclozine may be distributed into breast milk. However, problems in humans have not been documented. Due to its anticholinergic actions, Meclozine may inhibit lactation. Therefore, it is not recommended for lactating women unless the expected benefits outweigh any potential risk.
Pyridoxine is excreted into milk. While some have expressed concern over the inhibition of breast milk secretion by Pyridoxine, others have cautioned that Pyridoxine deficiency may cause seizures in neonate.
