Ultiva Caution For Usage

Incompatibilities: ULTIVA should only be reconstituted and diluted with those infusion solutions recommended (see Instructions for Use/Handling as follows).
It should not be reconstituted, diluted, or mixed with Lactated Ringer's Injection or Lactated Ringer's and 5% Dextrose Injection.
ULTIVA should not be mixed with propofol in the same infusion bag prior to administration.
Administration of ULTIVA into the same i.v. line with blood/serum/plasma is not recommended.
Non-specific esterase in blood products may lead to the hydrolysis of ULTIVA to its inactive metabolite.
ULTIVA should not be mixed with other therapeutic agents prior to administration.
Instructions for Use/Handling: ULTIVA is stable for 24 hours at room temperature (25°C) after reconstitution and further dilution to 20 to 250 micrograms/ml (50 micrograms/ml is the recommended dilution for adults and 20 to 25 micrograms/ml in paediatric patients aged 1 year and over) with one of the following i.v. fluids listed as follows: sterilised water for injections; 5% dextrose injection; 5% dextrose and 0.9% sodium chloride injection; 0.9% sodium chloride injection; 0.45% sodium chloride injection.
ULTIVA has been shown to be compatible with the following i.v. fluids when administered into running i.v. infusion of: Lactated Ringer's injection; Lactated Ringer's and 5% dextrose injection.
ULTIVA has been shown to be compatible with propofol when administered into running i.v. infusion.
The following tables give guidelines for infusion rates of ULTIVA. (See Tables 6, 7, 8, 9 and 10.)

Click on icon to see table/diagram/image


Click on icon to see table/diagram/image


Click on icon to see table/diagram/image


Click on icon to see table/diagram/image


Click on icon to see table/diagram/image