Adult General anaesth induction 0.5-1 mcg/kg/min w/ or w/o initial bolus infusion of 1 mcg/kg over not <30 sec.
Maintenance Dosage may be decreased individually & supplemental bolus infusion may be administered every 2-5 min.
Spontaneously breathing anaesthetised patient w/ secured airway Initially 0.04 mcg/kg/min.
Continuation into immediate post-op period Patient breathing spontaneously Initially, decrease infusion rate to 0.1 mcg/kg/min, may then be increased or decreased by not >0.025 mcg/kg/min every 5 min.
Cardiac anaesth induction Initially 1 mcg/kg/min.
Maintenance 0.5 mcg/kg.
Intensive care patient Initially 0.1-0.15 mcg/kg/min, titrated in increments of 0.025 mcg/kg/min. Further increase in increments of 0.025 mcg/kg/min if additional analgesia is required.
Additional analgesia for ventilated patient undergoing stimulation procedures Maintain 0.1 mcg/kg/min for at least 5 min prior to procedure, may be adjusted every 2-5 min. Max: 0.75 mcg/kg/min.
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