Hylan G-F 20 should not be used if there is a large intra-articular effusion prior to the injection.
As with any invasive joint procedure, it is recommended that the patient avoid any strenuous activities following the intra-articular injection, and resume full activities within a few days.
Hylan G-F 20 has not been tested in pregnant women or children under 18 years of age.
Hylan G-F 20 contains small amounts of avian protein and should not be used in patients with related hypersensitivities.