Dextromethorphan HBr occasionally causes drowsiness, dizziness, excitation, mental confusion and gastrointestinal disturbances. Very high doses may produce respiratory depression.
Other adverse reactions are:
General: Urticaria, drug rash, anaphylactic shock, photosensitivity, excessive perspiration, chills, dryness of mouth, nose and throat.
Cardiovascular system: Hypertension, headache, palpitations, tachycardia, extrasystoles.
Hematologic system: Hemolytic anaemia, thrombocytopenia, agranulocytosis.
Nervous system: Sedation, sleepiness, dizziness, disturbed coordination, fatigue, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, euphoria, paresthesia, blurred vision, diplopia, vertigo, tinnitus, acute labyrinthitis, hysteria, neuritis, convulsions.
G.I. system: Epigastric distress, anorexia, nausea, vomiting, diarrhoea, constipation.
G.U. system: Urinary frequency, difficult urination, urinary retention, early menses.
Respiratory system: Thickening of bronchial secretions, tightness of chest, wheezing and nasal stuffiness.