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Hypersensitivity to doxorubicin or any other component of the product, other anthracyclines or anthracenediones.
Pregnancy and lactation (see Precautions).
Contraindications for intravenous (IV) use: persistent myelosuppression or severe stomatitis induced by previous treatment with other antitumour agents or by radiotherapy; presence of generalised infection; severe arrhythmias; severe myocardial insufficiency; recent myocardial infarction; severe liver impairment; previous treatment with maximum cumulative doses of doxorubicin, daunorubicin, epirubicin, idarubicin and/or other anthracyclines and anthracenediones (see Precautions).
Contraindications for intravesical use: invasive tumours that have penetrated the bladder wall; urinary infections; inflammation of the bladder; catheterisation of the bladder (e.g., due to massive intravesical tumours); haematuria.
