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Incompatibilities: Doxorubicin should not be mixed with heparin as a precipitate may form and it is not recommended that Doxorubicin be mixed with other drugs. Contact with any solution of an alkaline pH should be avoided as it will result in hydrolysis of the drug. Doxorubicin should not be mixed with fluorouracil (e.g. in the same IV infusion bag or at the Y-site of an IV infusion line) since it has been reported that these drugs are incompatible to the extent that a precipitate might form. If concomitant therapy with Doxorubicin and fluorouracil is required, it is recommended that the IV line be flushed between the administrations of these drugs.
Special precautions for disposal: Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
