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Instructions for Use/Handling: Syrup: No special instructions are required.
IV infusion: RETROVIR I.V. for Infusion must be diluted prior to administration.
Since no antimicrobial preservative is included, dilution must be carried out under full aseptic conditions, preferably immediately prior to administration, and any unused portion of the vial should be discarded.
The required dose should be added to and mixed with Glucose Intravenous Infusion 5% w/v to give a final zidovudine concentration of either 2 mg/ml or 4 mg/ml. These dilutions are chemically and physically stable for up to 48 hours at both 5°C and 25°C.
Should any visible turbidity appear in the product either before or after dilution or during infusion, the preparation should be discarded.
Incompatibilities: Syrup: None known.
IV infusion: No data.
