Repatha Patient Counseling Information

Advise the patient and/or caregiver to read the patient labeling [Patient Information and Instructions for Use (IFU)] before the patient starts using REPATHA, and each time the patient gets a refill as there may be new information they need to know.
Hypersensitivity: Inform patients that serious hypersensitivity reactions (e.g., angioedema) have been reported in patients treated with REPATHA. Advise patients on the symptoms of hypersensitivity reactions and instruct them to discontinue REPATHA and seek medical attention promptly, if such symptoms occur.
Administration: Provide guidance to patients and caregivers on proper subcutaneous administration technique, including aseptic technique, and how to use the single-use pre-filled autoinjector correctly (see Instructions for Use leaflet). Inform patients that it may take up to 15 seconds to administer REPATHA using the single-use pre-filled autoinjector.
Latex-Sensitivity: Advise latex-sensitive patients that the needle cover of the single-use pre-filled autoinjector contain dry natural rubber (a derivative of latex) that may cause allergic reactions in individuals sensitive to latex.