Repatha Indications/Uses

Prevention of Cardiovascular Events: REPATHA is indicated as an adjunct to diet and standard of care therapy (including moderate- to high-intensity statin therapy alone or in combination with other lipid-lowering therapy), to reduce the risk of myocardial infarction, stroke, and coronary revascularization in adult patients with atherosclerotic cardiovascular disease.
Primary Hyperlipidemia (Including Heterozygous Familial Hypercholesterolemia): REPATHA is indicated for the reduction of elevated low-density lipoprotein cholesterol (LDL-C) in adult patients with primary hyperlipidemia (including heterozygous familial hypercholesterolemia [HeFH]): as an adjunct to diet and statin therapy, with or without other lipid-lowering therapies, in patients who require additional lowering of LDL-C; as an adjunct to diet, alone or in combination with non-statin lipid-lowering therapies, in patients for whom a statin is contraindicated.
Pediatric Patients with Heterozygous Familial Hypercholesterolemia: REPATHA is indicated as an adjunct to diet and other LDL-C-lowering therapies (e.g., statins, ezetimibe) in pediatric patients aged 10 years and older with HeFH who require additional lowering of LDL-C.
Homozygous Familial Hypercholesterolemia: REPATHA is indicated as an adjunct to diet and other LDL-lowering therapies (e.g., statins, ezetimibe, LDL apheresis) in adult and pediatric patients aged 10 years and older with homozygous familial hypercholesterolemia (HoFH) who require additional lowering of LDL-C.