Sign Out
For both hypertension and angina, the usual initial dose is 5 mg amlodipine once daily, which may be increased to a maximum dose of 10 mg depending on the individual patient's response.
No dose adjustment of amlodipine is required upon concomitant administration of thiazide diuretics, beta-blockers, and ACE inhibitors.
Use in the Elderly: Normal dosage regimens are recommended. Amlodipine, used at similar doses in the elderly or younger patients, is equally well tolerated.
Use in Children: Children and adolescents with hypertension from 6 years to 17 years of age. The recommended antihypertensive oral dose in pediatric patients aged 6-17 years is 2.5 mg once daily as a starting dose, up-titrated to 5 mg once daily if blood pressure goal is not achieved after 4 weeks. Doses in excess of 5 mg daily have not been studied in pediatric patients (see Pharmacology: Pharmacodynamics and Pharmacokinetics under Actions).
Children under 6 years old: No data are available.
Use in Patients with Impaired Hepatic Function: See Precautions.
Use in Patients with Renal Failure: Amlodipine may be used at normal doses in patients with renal failure. Changes in amlodipine plasma concentrations are not correlated with the degree of renal impairment. Amlodipine is not dialyzable.
