Maxigesic is contraindicated for use: in patients with known hypersensitivity reaction to paracetamol, ibuprofen, aspirin, other NSAIDs or any other ingredients in the product;
in patients with active alcoholism as chronic excessive alcohol ingestion may predispose patients to paracetamol hepatoxicity (due to the paracetamol component);
in patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin, ibuprofen or other NSAIDs. Severe, rarely fatal, anaphylactic-like reactions to NSAIDs have been reported in such patients (see Pre-existing Asthma under Precautions);
in patients with active gastrointestinal bleeding, peptic ulceration or other stomach disorders;
during pregnancy or in patients planning to become pregnant;
during breastfeeding;
in patients with impaired kidney function, impaired liver function or heart problems.