Maxigesic Adverse Reactions

Clinical trials with Maxigesic have not indicated any other undesirable effects other than those for paracetamol alone or ibuprofen alone.
Side effects of paracetamol are rare and usually mild, although haematological reactions have been reported.
Cutaneous hypersensitivity reactions including skin rashes, angioedema, Stevens Johnson Syndrome/Toxic Epidermal Necrolysis have been reported.
Overdosage with paracetamol if left untreated can result in severe, sometimes fatal liver damage and rarely, acute renal tubular necrosis.
Adverse effects with non-prescription (OTC) or short-term use ibuprofen are rare and may include: gastrointestinal - gastrointestinal bleeding, dyspepsia, heartburn, nausea, loss of appetite, stomach pain, diarrhoea.
central nervous system (CNS) - dizziness, fatigue, headache, nervousness.
hypersensitivity reactions - skin rashes and itching. Rarely exfoliative dermatitis and epidermal necrolysis have been reported with ibuprofen.
rare cases of photosensitivity.
cardiovascular - risks of myocardial infarct and stroke. These risks are minimal at Maxigesic recommended maximum daily doses but increase with longer duration of treatment, and in the elderly. Fluid retention and in some cases oedema have been reported with all NSAIDs. These effects are rare at non-prescription doses.
Allergic reactions such as skin rash, itching, swelling of the face or breathing difficulties may also occur. These are usually transient and reversible on cessation of treatment.