Chronic inflammatory bowel disease and/or bowel obstruction (see Precautions).
Hypersensitivity to the active substance(s) or to any of the excipients.
Lactation (see Use in Pregnancy & Lactation).
Bilirubin > 3 times the upper limit of the normal range (see Precautions).
Severe bone marrow failure.
WHO performance status > 2.
Concomitant use with St John's Wort (see Interactions).
Live attenuated vaccines (see Interactions).
For additional contraindications of cetuximab or bevacizumab or capecitabine, refer to the product information for these medicinal products.