Imbruvica Description

IMBRUVICA 140mg hard capsules: Each hard capsule contains 140 mg of ibrutinib.
IMBRUVICA 140mg film-coated tablets: Each film-coated tablet contains 140 mg of ibrutinib.
IMBRUVICA 280mg film-coated tablets: Each film-coated tablet contains 280mg of ibrutinib.
IMBRUVICA 420mg film-coated tablets: Each film-coated tablet contains 420mg of ibrutinib.
Excipients/Inactive Ingredients: Capsules: Capsule content: Croscarmellose sodium, Magnesium stearate, Microcrystalline cellulose, Sodium lauril sulfate (E487).
Capsule shell: Gelatin, Titanium dioxide (E171).
Printing ink: Shellac, Black iron oxide (E172), Propylene glycol (E1520).
Film-coated tablets: Excipients with known effect: Each 140mg film-coated tablet contains 28mg of lactose monohydrate.
Each 280mg film-coated tablet contains 56mg of lactose monohydrate.
Each 420mg film-coated table contains 84mg of lactose monohydrate.
Tablet core: Colloidal anhydrous silica, Croscarmellose sodium, Lactose monohydrate, Magnesium stearate, Microcrystalline cellulose, Povidone, Sodium lauril sulfate (E487).
Film-coat: IMBRUVICA 140mg film-coated tablet and IMBRUVICA 420mg film-coated tablets: Macrogol, Polyvinyl alcohol, Talc, Titanium dioxide (E171), Black iron oxide (E172), Yellow iron oxide (E172).
IMBRUVICA 280mg film-coated tablets: Macrogol, Polyvinyl alcohol, Talc, Titanium dioxide (E171), Black iron oxide (E172), Red iron oxide (E172).