Healthy volunteers were treated for three months with an oral dose of 11.2 g of acetylcysteine per day without any serious undesirable effects being observed. Oral doses of up to 500 mg acetylcysteine per kg body weight have been tolerated without any signs of toxicity.
Symptoms: Overdose may lead to gastrointestinal effects such as nausea, vomiting and diarrhoea.
Treatment: There are no antidotes to acetylcysteine and treatments are symptomatic.