Factive can be taken with or without food and should be swallowed whole with a liberal amount of liquid. The recommended dose of Factive is 320 mg daily, according to following indication. (See Table 2.)
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Table 3 as follows provide dosage guidelines for use in renal impaired patients. (See Table 3.)
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Adequate hydration of patients receiving FACTIVE should be maintained to prevent the formation of highly concentrated urine.
Other special populations: Dosage adjustment in elderly patients or patients with hepatic impairment is not required.