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Patients who develop antibody-mediated Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin should not receive Eprex or any other erythropoietin (See Precautions, Pure Red Cell Aplasia).
Uncontrolled hypertension.
Hypersensitivity to the active substance or to any of the excipients.
All contraindications associated with autologous blood predonation programs should be respected in patients being supplemented with Eprex.
The use of Eprex in patients scheduled for major elective orthopedic surgery and not participating in an autologous blood predonation program is contraindicated in patients with severe coronary, peripheral arterial, carotid or cerebral vascular disease, including patients with recent myocardial infarction or cerebral vascular accident.
Surgery patients who for any reason cannot receive adequate antithrombotic prophylaxis.
