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Pregnancy: Experimental and clinical investigations give no indication that Cotren vaginal tablets has any harmful effects on the mother and child when administered during pregnancy. Sanitation of the birth canal should be ensured particularly during the last 4-6 weeks of pregnancy.
During pregnancy the Cotren vaginal tablets should be inserted without using an applicator.
Administration during the first trimester of pregnancy should be used with clear indication.
Lactation: Available pharmacodynamic/toxicological data in animals have shown excretion of clotrimazole/metabolites in milk. Breast-feeding should be discontinued during treatment with clotrimazole.
