Cotren Special Precautions

Medical advice should be sought if this is the first time the patient has experienced symptoms of candidal vaginitis. Before using Cotren vaginal tablets, medical advice must be sought if any of the following are applicable: more than two infections of candidal vaginitis in the last six months; previous history of a sexually transmitted disease or exposure to partner with sexually transmitted disease; pregnancy or suspected pregnancy; aged under 16 or over 60 years; known hypersensitivity to imidazoles or other vaginal antifungal products.
Cotren vaginal tablets should not be used if the patient has any of the following symptoms whereupon medical advice should be sought: irregular vaginal bleeding; abnormal vaginal bleeding or a blood-stained discharge; vulval or vaginal ulcers, blisters or sores; lower abdominal pain or dysuria; any adverse events such as redness, irritation or swelling associated with the treatment; fever or chills; nausea or vomiting; diarrhoea; foul smelling vaginal discharge.
Patients should be advised to consult their physician if the symptoms have not been relieved within one week of using Cotren vaginal tablets. The pessaries can be used again if the candidal infection returns after 7 days. However, if the candidal infection recurs more than twice within six months, patients should be advised to consult their physician.
Effects on Ability to Drive and Use Machine: The medication has no or negligible influence on the ability to drive or use machinery.