Clobet Special Precautions

Long term continuous therapy with CLOBET CREAM in infants and children should be avoided since it may induce adrenal suppression.
It should not be used extensively in pregnancy, either in large amounts or for prolonged periods.
Appropriate chemotherapy should be used whenever secondary infections occured.
If used in childhood or on the face, courses should be limited if possible to 5 days and occlusion should not be used.
The face, more than other areas of the body, may exhibit atrophic changes after prolonged treatment with potent topical corticosteroids. This must be borne in mind when treating such conditions as psoriasis, discoid lupus erythematosus and severe eczema.
If applied to the eyelids, care is needed to ensure that the preparation does not enter the eye, as glaucoma might result.
Topical corticosteroids may be hazardous in psoriasis for a number of reasons including rebound relapses, development of tolerance, risk of generalised pascular psoriasis and development of local or systemic toxicity due to impaired barrier function of the skin.
If used in psoriasis, careful patient supervision is important.