Provagin Mechanism of Action

Metronidazole is bactericidal, amoebicidal and trichomonaside. The mechanism of action cannot be assured yet.
Metronidazole is not ionized at physiological pH and is ready to be taken by organisms or anaerobic cells. In susceptible organisms or cells, Metronidazole undergoes a reduction process by low redox potential electron transport proteins (eg, nitroreductase such as ferredoxin) into polar products that have lost the nitro group so that it is not known. This reduction product is responsible for the cytotoxic and antimicrobial effects of Metronidazole, which includes interference with DNA and inhibition of nucleic acid synthesis. Metronidazole is as effective as cells whether it is splitting or not.
Nystatin acts as a fungistatic and fungicides, it works by binding the sterols (especially ergosterol) in the cell membranes of fungi. Nystatin is not active against organisms (eg, bacteria) that do not have sterols on their cell membranes. The results of this bond make the cell membrane no longer function as a selective barrier, and potassium and other components will disappear. The main effectiveness of Nystatin is to against Candida (Monilia) spp.