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Atenolol may increase the hypoglycaemic effect of insulin and other antidiabetic drugs, cardiodepressant effect of calcium antagonists, antiarrhythmias and anaesthetic drugs.
Combined use of β-blocker with calcium antagonists, nitrates, hypnotics, nueroleptics and diuretics may cause a hypotensive effect.
Combination with clonidine may cause hypertension if suddenly withdrawn.
