Gynprogest Special Precautions

Prior to taking hormone replacement therapy (and at regular intervals thereafter) each woman should be assessed. A personal and family medical history should be taken and physical examination should be guided by this and by the contraindications and warnings for this product.
Gynprogest should not be taken with food and should be taken at bedtime. Concomitant food ingestion increases the bioavailability of Gynprogest.
Gynprogest should be used cautiously in patients with conditions that might be aggravated by fluid retention (e.g. hypertension, cardiac disease, renal disease, epilepsy, migraine, asthma); in patients with a history of depression, diabetes, mild to moderate hepatic dysfunction, migraine or photosensitivity and in breastfeeding mothers.
Clinical examination of the breasts and pelvic examination should be performed where clinically indicated rather than as a routine procedure. Women should be encouraged to participate in the national breast cancer screening programme (mammography) and the national cervical cancer screening programme (cervical cytology) as appropriate for their age. Breast awareness should also be encouraged and women advised to report any changes in their breasts to their doctor or nurse.
Effects On Ability To Drive And Use Machines: Gynprogest may cause drowsiness and/or dizziness in a minority of patients; therefore caution is advised in drivers and users of machines. Taking the capsules at bedtime should reduce these effects during the day.
Use in Pregnancy: The use of Gynprogest is not contraindicated during pregnancy including the first few weeks.
Use in Lactation: Detectable amounts of progesterone enter the breast milk. There is no indication for prescribing HRT during lactation.