Use in pregnancy & lactation: Although some dihydropyridine compounds have been found to be teratogenic in animals, data in rat and rabbit for amlodipine provide no evidence for a teratogenic effect. There is, however, no clinical experience with Amedin in pregnancy or lactation. Accordingly, Amedin should not be administered during pregnancy, or lactation, or to women of childbearing potential unless effective contraception is used.